34550 Biomedical optics
Point( ECTS )
Taught under single-course student
|Technological specialization course, MSc. Eng., Medicine and Technology |
Technological specialization course, MSc. Eng., Photonics
Technological specialization course, MSc. Eng., Physics and Nanotechnology
|E4A (Tues 13-17)
Scope and form:
|Lectures and group work|
Duration of Course:
Type of assessment:
| , |
General course objectives:
The interest for applications of coherent light and optical sensing
in biology and medicine has been increasing the past years. This is
partly due to the development of new laser systems, partly the
development in optical systems and finally advances in precise and
non-invasive diagnostics and analyses. The course is divided into
three areas: 1) Light sources for medical diagnostics and
treatment, 2) light-tissue interactions, and 3) Optical methods for
A student who has met the objectives of the course will be able to:
- Discuss basic optical principles like coherence, interference
and diffraction, and determine imaging properties of simple rays in
spherical lenses and mirrors.
- Explain the principle of laser action and understand the mode
of operation of the various components in different laser
- Discuss the physics behind nonlinear frequency conversion, and
describe tuning properties of coherent light sources based on
nonlinear frequency conversion.
- Explain different light-tissue interactions, e.g.:
Photochemical, thermal, photo induced plasma and photo ablation,
and be able to relate these interactions to the characteristics of
the light source.
- Discuss the optical properties of tissue (scattering and
absorption) and the wavelength dependencies of these
- Describe the principle of transport theory and knowledge of
solutions, including diffusion theory.
- Apply the principle of Monte Carlo simulations as a general
solution and understand how this method can be used to solve
transport theory of light propagation in scattering media.
- Explain and discuss the functionality of a specific optically
based diagnostic system, OCT, and two-photon microscopy
- Describe spectroscopic techniques such as fluorescence,
two-photon microscopy, and Raman spectroscopy, and understand the
basic operation and limitations of a spectrometer.
- Orally present scientific papers within the areas of the course
and discuss results.
The lectures will cover the biological and medical background for
application of light for treatment and diagnosis, especially
propagation of light in human tissue, interaction between light and
tissue, possibilities for therapy with light and imaging methods.
An important topic is the optical properties of the eye: Spectral
properties, fluorescence of the various parts of the eye, optical
diagnostics by scattered light within the eye, properties of the
retina and possibilities for healing by optical treatment. Further,
modern coherent light sources will be covered such as the optical
properties of laser beams, different laser systems and their
potential for bio-medical applications. Throughout the course
examples and external visits will be used whenever possible.
Lecturers from DTU Fotonik, DTU Nutech, and a number of invited
Green challenge participation:
Please contact the teacher for information on whether this course
gives the student the opportunity to prepare a project that may
participate in DTU´s Study Conference on sustainability, climate
technology, and the environment (GRØN DYST). More infor
, Risø Campus, Building 108, Ph.
(+45) 4677 4579 ,
, Risø Campus, Building 108, Ph.
(+45) 4677 4555 ,
, Risø Campus, Building 201, Ph.
(+45) 4677 4969 ,
Department of Photonics Engineering|
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Last updated: 24. november, 2015