27334 Bioactive compounds and nutrigenomics
|Bioaktive stoffer og nutrigenomics|
Point( ECTS )
Taught under open university
Scope and form:
|Lectures, discussions of research papers, group work,
Duration of Course:
|Decide with teacher, No exam during the ordinary
Type of assessment:
General course objectives:
Please see the Danish version
A student who has met the objectives of the course will be able to:
- Define concepts related to nutrigenomics (gene polymorphism,
metagenome, epigenetics, gene transcription, proteome, and
- Define the term biomarkers in relation to health and
- Explain how the diet via effects on gut flora may affect the
health status of the body.
- Read scientific publications and relate critically to the
presented research methods and results.
- Employ knowledge about the immune system, biochemisty,
nutrition, and diseases to present hypotheses for how nutrients and
bioactive compounds can affect cell metabolism and activity
(mechanism of action).
- Combine and compare information from scientific articles to
assess the efficacy of a bioactive compound.
- Using computer-based tools analyze the potential effect of a
bioactive substance on the metabolism, and from this develop a
hypothesis for the mechanism of action.
- Clearly present and support a hypothesis orally and in
- Actively participate in an academic discussion on bioactive
compounds and their mechanisms of action.
The course consists of lectures and supervised project work, full
time for three weeks.
The course covers the following subjects:
Gene regulation - Individual variations in response to bioactive
compounds – The gut microbiota and human health - Chemical
properties of bioactive compounds – Nutrigenomics methods –
Biomarkers – Computer-based methods to asses bioactivity
In the first week of the course, critical reading of research
articles is practiced. Weeks 2-3 of the course will mainly focus on
project work concerning defined case studies including scientific
writing and oral presentation by each group. Selected research
literature, reviews and original papers, will be provided for the
different, predefined bioactivity-nutrigenomics topics of the
Green challenge participation:
Please contact the teacher for information on whether this course
gives the student the opportunity to prepare a project that may
participate in DTU´s Study Conference on sustainability, climate
technology, and the environment (GRØN DYST). More infor
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Last updated: 05. maj, 2014